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Understanding the Conical Penetration Test Method for Medical Vaseline
2023-05-22 16:56:02 admin 582
Vaseline is a semi liquid mixture of alkanes or saturated hydrocarbons, obtained by fractional distillation of petroleum. Its state is between solid and liquid at room temperature. Vaseline is classified into three categories based on its scope of use, physicochemical properties, and production requirements using internationally recognized product standards: pharmaceutical Vaseline, industrial Vaseline, and capacitor Vaseline. In China, a national standard for ordinary Vaseline (GB 6732-86) has been added.

Medical Vaseline is further divided into white Vaseline and yellow Vaseline according to its refining depth, and is an important raw material for medical ointments, ointments, and creams.

The fourth part of the 2015 Chinese Pharmacopoeia stipulates that white and yellow vaseline need to be inspected for cone penetration in accordance with General Rule 0983 for medicinal excipients. The cone penetration determination method specified in General Rule 0983 is applicable to semi solid substances such as ointments, eye ointments, and commonly used matrix materials (such as vaseline, lanolin, beeswax) to control their softness, hardness, viscosity, and other properties, and to avoid affecting the application ductility of drugs.

Consistency refers to the degree to which paste, cream, creamy, semi solid, or high viscosity samples resist deformation under stress. The method of measuring consistency is called penetration method, where the harder the test material, the sharper and closer the test head is to a needle shape.

How to choose the three types of cones specified in the pharmacopoeia

① I cone is recommended for testing samples of oil based matrices such as Vaseline

② For testing samples of emulsion based matrices, it is recommended to use No. II and No. III cones due to their low viscosity;

During this experiment, it is necessary for the operator to continuously summarize their experience and proficient skills in order to pursue better accuracy and repeatability. We recommend that you use both the ST211A manual and ST211B automatic petroleum cone penetration testers, which are designed and manufactured using the latest pharmacopoeia 0983 cone penetration measurement method from 2020.



The ST211A manual constant temperature cone penetration tester is designed and manufactured in accordance with the technical requirements and relevant regulations of the 2020 Pharmacopoeia 0983 cone penetration measurement rule. It is mainly suitable for semi solid substances such as ointments, eye ointments, and commonly used matrix materials (such as Vaseline, Lanolin, Beeswax) to control their softness, hardness, viscosity, and other properties to avoid affecting the coating ductility of drugs.

Main technical features

1. Using a digital display to display the cone penetration value, it is intuitive and eye-catching.

2. Equipped with coarse and fine adjustment functions for the lifting frame, easy adjustment and accurate needle alignment.

3. Equipped with a heating and cooling constant temperature bath, the water bath temperature is automatically controlled, and the instrument has a high cost-effectiveness.



The ST211B fully automatic constant temperature cone penetration tester is designed and manufactured according to the technical requirements and relevant regulations of the 2020 Pharmacopoeia 0983 cone penetration measurement rule. It is mainly suitable for testing the cone penetration of Vaseline and ointment. With a microprocessor as the core, integrating mechanical, optoelectronic, and micro detection technology, the lifting arm automatically lifts, the touch screen fine adjusts the distance, automatically determines the results, and automatically prints.

Main technical features

1. Upgrade to a 7-inch TFT color LCD display;

2. Constant temperature cooling method: external semiconductor cooling.

3. Detection method: high-precision displacement sensor.

4. After upgrading, it can store 199 sets of historical data for easy query; Simultaneous USB drive output function

5. Standard micro printer for automatic measurement and printing